EDK
Editome Disease Knowledgebase
Head and Neck Cancer
| Disease name | Head and Neck Cancer |
|---|---|
| Classfication | Cancer |
| Related Enzyme(s) | |
| EFO | - |
| DOID | 11934 |
| OMIM | |
| NCI | |
| Definition | Head and neck cancer is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands. |
| Gene symbol | Disease | Enzyme | Editing Sites | Editing Type | miRBase | PMID | Description |
|---|---|---|---|---|---|---|---|
| hsa-miR-200b | ADAR1;ADAR2 | 1 | A-to-I | MI0000342 | miR-200b editing shows correlations with TP53 in breast cancers. High editing level in miR-200b is associated with worse patient survival. | ||
| hsa-miR-99a | ADAR1;ADAR3 | 1 | A-to-I | MI0000101 | miR-99a editing shows correlations with TP53, HRAS, MAP3K1, PIK3CA in breast cancer, head and neck cancer, thyroid cancer. |